کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1169681 960646 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Application of liquid–liquid–liquid microextraction and high-performance liquid-chromatography for the determination of sulfonamides in water
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Application of liquid–liquid–liquid microextraction and high-performance liquid-chromatography for the determination of sulfonamides in water
چکیده انگلیسی

This work presents a novel liquid–liquid–liquid microextraction (LLLME) technique for the extraction of sulfonamides from aqueous systems; it combines with high-performance liquid-chromatography-ultraviolet absorbance detection (HPLC/UV). In this experiment the sulfonamides were successively extracted from a donor phase (i.e., a water sample) into several microliters of an organic phase and then from the organic phase into an acceptor phase (i.e., an aqueous extract) by LLLME. The following separation and quantitative analyses were performed using HPLC/UV with 265 nm detection. Extraction condition such as solvent identity, agitation, extraction time, acceptor phase NaOH concentration, donor phase pH, and salt addition were optimized. Relative standard deviation (RSD, 2.6–5.3%), coefficient of estimation (R2, 0.9972–0.9999), and method detection limit (MDL, 0.11–0.77 ng mL−1) were achieved under the selected conditions. The proposed method was successfully applied to the analyses of three practical water samples and the relative recoveries of sulfonamides from the spiked water samples were in the range of 86.2–108.7%. The proposed method also confirms microextraction to be robust to monitoring trace levels of sulfacetamide, sulfadiazine, sulfathiazole, sulfamerazine, sulfadimidine, sulfamonomethoxine, sulfamethoxazole, and sulfaquinoxaline in aqueous samples.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytica Chimica Acta - Volume 612, Issue 1, 31 March 2008, Pages 37–43
نویسندگان
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