کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1170102 960665 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A dual detector capillary waveguide biosensor for detection and quantification of hybridized target
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
A dual detector capillary waveguide biosensor for detection and quantification of hybridized target
چکیده انگلیسی

We describe a novel technique for improving the sensitivity of analytical instruments based on the measurement of fluorescent intensity. Independent measurement of the Rayleigh scattered intensity component by means of a second photodetector leads to normalized data, which are independent of various experimental parameters. Incorporation of this technique into a fully automated capillary waveguide biosensor improved the instrument sensitivity by a factor of three. The technique enables quantification, as well as detection, of the hybridized target molecules.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytica Chimica Acta - Volume 598, Issue 1, 15 August 2007, Pages 147–154
نویسندگان
, , , , , ,