کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1172290 1491183 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Preparation of a novel fluorescence probe based on covalent immobilization by emulsion polymerization and its application to the determination of metronidazole
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Preparation of a novel fluorescence probe based on covalent immobilization by emulsion polymerization and its application to the determination of metronidazole
چکیده انگلیسی

A novel method of preparing fluorescence particle probe by emulsion polymerization with covalent immobilization of indicator dye was described. A terminal double bond was attached to 3-amino-9-ethylcarbazole (AEC) via methacryloyl chloride, and the resultant compound was copolymerized with butyl methacrylate. The obtained polymer particles were used as a fluorescence probe, which is almost free of dye leaching, and has higher photostability and lower toxicity in comparison with free AEC. This probe holds great potential for the applications in intracellular measurements. In present study the prepared probe was used for the determination of metronidazole. The results revealed that the probe showed good selectivity and had a linear response to the analyte in the range from 2.0 × 10−5 to 1.0 × 10−3 mol l−1 with a detection limit of 9.0 × 10−6 mol l−1.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytica Chimica Acta - Volume 560, Issues 1–2, 23 February 2006, Pages 191–196
نویسندگان
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