کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1180385 1491453 2008 26 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Acetogenesis and the Wood–Ljungdahl pathway of CO2 fixation
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Acetogenesis and the Wood–Ljungdahl pathway of CO2 fixation
چکیده انگلیسی

Conceptually, the simplest way to synthesize an organic molecule is to construct it one carbon at a time. The Wood–Ljungdahl pathway of CO2 fixation involves this type of stepwise process. The biochemical events that underlie the condensation of two one-carbon units to form the two-carbon compound, acetate, have intrigued chemists, biochemists, and microbiologists for many decades. We begin this review with a description of the biology of acetogenesis. Then, we provide a short history of the important discoveries that have led to the identification of the key components and steps of this usual mechanism of CO and CO2 fixation. In this historical perspective, we have included reflections that hopefully will sketch the landscape of the controversies, hypotheses, and opinions that led to the key experiments and discoveries. We then describe the properties of the genes and enzymes involved in the pathway and conclude with a section describing some major questions that remain unanswered.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics - Volume 1784, Issue 12, December 2008, Pages 1873–1898
نویسندگان
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