کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1181928 1491638 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Preparation and Characterization of Polymer Solid-phase Extraction Monolith Immobilized Metal Affinity Ligands
ترجمه فارسی عنوان
آماده سازی و شناسایی پلی مری استخراج فاز جامد مونولیت متخلخل فلزی متخلخل
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی

Based on the affinity interactions between Cu2+ metal chelate and -SH groups of aminothiols such as cysteine, a polymer solid-phase extraction (SPE) monolith was designed and synthetized by the tridentate ligand iminodiacetic acid immobilized on the surface of poly glycidyl methacrylate-based monolith and after modification with Cu2+. Glutathione as a model compound was tested to evaluate the performance of the SPE monolith, and optimized to the enrichment conditions. Under the optimum conditions, the maximum absorption capacity for glutathione of this polymer SPE monolith was determined at 43.15 mg g−1, and the polymer monolith was used for the extraction and enrichment of trace aminothiols in human plasma samples.

On the basis of the affinity interactions between Cu2+ of metal chelate and –SH groups of aminothiols such as cysteine, a polymer solid-phase extraction monolith was designed and synthesized by immobilizing the tridentate ligand iminodiacetic acid (IDA) on the surface of poly glycidyl methacrylate-based monolith after modification with Cu2+. The synthesized polymer monolith was used for the extraction and enrichment of trace aminothiols in human plasma samples.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Journal of Analytical Chemistry - Volume 42, Issue 4, April 2014, Pages 495–500
نویسندگان
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