Determination of Bisphenol A in Plastic Bottled Drinking Water by High Performance Liquid Chromatography with Solid-membrane Extraction Based on Electrospun Nylon 6 Nanofibrous Membrane

A new method for determining bisphenol A (BPA) in plastic bottled drinking water was developed by the combination of electrospun nylon6 nanofibers membrane-based solid-phase extraction with high performance liquid chromatography-ultraviolet (HPLC-UV) detector. Important parameters affecting extraction efficiency such as eluant and its volume, flow rate of sample, sample volume, pH value of sample, the amount of membrane and the reusability of this membrane were optimized. Results indicate that 10 mL of water sample volume passed through nylon6 nanofibrous membrane at a flow rate of 3.0 mL min−1, only 1.5 mg of membrane and 300 μL of eluant were sufficient for the adsorption and desorption of BPA in the samples. Each piece of this membrane could be used at least 6 times. Under optimized conditions, an excellent linear relationship in a range of 0.2–20 μg L−1 with determined coefficient (r) 0.9998 was obtained, the limits of detection for BPA was 0.15μg L−1. The relative standard deviation (RSD %) of intramembrane and intermembrane with nylon6 nanofibrous membrane were all less than 4.5% (n = 6). The proposed method has been applied to the analysis of plastic bottled purified water of six different brands. Satisfactory recovery (95.0%) was obtained at a spiked level of 1.0 μg L−1. BPA was detected via a range of 0.20–0.30 μg L−1. A comparison between the solid-membrane extraction (SME) via nylon6 nanofibrous membrane and SPE via other sorbents used in literatures was carried out. All the results indicate that as a novel material nylon6 nanofibrous membrane has a great potential for the enrichment and determination of BPA in water.