New Developments of Quantitative Mass Spectrometry-based Proteomics

Mass spectrometry has become a powerful technology for proteome analysis. It would be highly desirable to obtain an exact quantitative value and the dynamic data of each protein in a system for providing important information to study protein function, to reveal the biological process and to discover protein biomarker and drug target. In this paper, the developments of quantitative mass spectrometry-based proteomics on strategy, method and application in recent years with further addressed characteristics and potentialities in protein analysis are discussed.