Application of Atom Transfer Radical Polymerization in Biosensing

Atom transfer radical polymerization (ATRP) is a novel class of signal amplification method. In polymerization process, monomers accumulate and grow up to form long-chain polymers with abundant electroactive or photoactive groups for coupling other molecules, resulting in the distinct increase of the loading of signal molecules and the detection sensitivity. This article reviewed the mechanism of ATRP, and summarized the recent applications of ATRP in biosensing. Particularly, future studies and prospects were envisioned.