Preparation of Nano-Copper Modified Glassy Carbon Electrode and Its Catalytic Oxidation to Glucose

Nano-Cu modified glassy carbon electrode (nano-Cu-GCE) fabrication by reduction of CuSO4 in the presence of cetyltrimethylammonium bromide (CTMAB), through potentiostatic process, and catalytic oxidation of glucose on the nano-Cu-GCE were proposed. Optimum potential and time for deposition of Cu were –100 mV and 8 min, respectively. The potential used for the determination of glucose was 400 mV. The results indicated that nano-Cu-GCE showed an improved catalytic activity on oxidation of glucose compared with the electrode obtained in the absence of CTMAB. Current increment Δi upon addition of glucose was linear with concentrations of glucose in the range of 1.0 × 10−6–3.9 × 10−4 M in 0.1 M NaOH solution with a detection limit of 2.6 × 10−7 M (S/N = 3). Ascorbic acid (AA), para-acetaminophen (AP), and L-cysteine (Cys) had almost no interference in the glucose response.