کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1186429 | 963438 | 2010 | 6 صفحه PDF | دانلود رایگان |
Male hamsters were fed six different diets for 4 weeks. Group 1, fed with control diet of regular rodent chow. Group 2, fed with high-fat-high-cholesterol diet containing cholesterol and corn/coconut oil mixture. Group 3, the positive control fed with high-fat-high-cholesterol diet containing 0.74% (w/w) phytosterols. Groups 4–6 were the high-fat-high-cholesterol diet mixed with phytosterol-containing lactic-fermented milk powder (PSFMP) which contains 0.37%, 0.74% and 1.85% (w/w) of phytosterols, respectively. Results demonstrated that PSFMP could significantly decrease (P < 0.05–P < 0.001) the levels of total cholesterol (serum cholesterol), serum triacylglycerol, liver lipids and atherogenic index (LDL-C/HDL-C), while it could also significantly (P < 0.001) increase the level of fecal cholesterol. The pronounced hypolipidemic effects of PSFMP might be attributed to its ability to enhance cholesterol excretion. These results suggest that PSFMP could be used as a potential cholesterol-lowering ingredient in the management of hypercholesterolemia.
Journal: Food Chemistry - Volume 119, Issue 3, 1 April 2010, Pages 1121–1126