کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1188771 963497 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Optimisation of hydrolysis conditions for the production of the angiotensin-I converting enzyme (ACE) inhibitory peptides from whey protein using response surface methodology
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Optimisation of hydrolysis conditions for the production of the angiotensin-I converting enzyme (ACE) inhibitory peptides from whey protein using response surface methodology
چکیده انگلیسی

In the present research, the effect of process conditions on the angiotensin-I converting enzyme (ACE) inhibitory activity of whey protein concentrate hydrolysed with crude proteinases preparation from L. helveticus LB13 was investigated systematically using response surface methodology. It was shown that ACE inhibitory activity of the whey hydrolysates could be controlled by regulation of three process conditions (hydrolysis temperature, pH and enzyme to substrate (E/S) ratio). Hydrolysis conditions for optimal ACE inhibition were defined using a response surface model. E/S ratio at 0.60, pH at 9.18 and temperature at 38.9 °C were found to be the optimal conditions to obtain high ACE inhibitory activity close to 92.2% and DH of the whey protein was 18.8%.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 114, Issue 1, 1 May 2009, Pages 328–333
نویسندگان
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