کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1190464 | 1492159 | 2007 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: DNA damage protecting activity and antioxidant potential of pudina extract DNA damage protecting activity and antioxidant potential of pudina extract](/preview/png/1190464.png)
Pudina extract (Mentha spicata Linn.) used as flavoring in culinary preparation throughout the plains of India was examined for its DNA damage protecting activity and antioxidant potential. n-Butanol soluble fraction (PE) derived from methanol extract of Mentha spicata Linn. at 10 μg/ml exhibited significant protecting activity against DNA strand scission by OH on pBluescript II SK(–) DNA. IC50 concentration of PE to scavenge DPPH, ABTS+ and superoxide radical was 7.47, 4.05 and 57.80 μg/ml, respectively. Inhibition of lipid peroxidation induced with 25 mM FeSO4 on rat liver homogenate as lipid source was noted at 500 μg/ml of PE with Antioxidant Index of 63.43%. Total polyphenol content of one-milligram pudina extract was equivalent to 500 μg of gallic acid. Therefore, this potential bioactivity of pudina extract was associated with its high polyphenolic content.
Journal: Food Chemistry - Volume 100, Issue 4, 2007, Pages 1377–1384