کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1200141 1493630 2013 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
In situ aqueous derivatization as sample preparation technique for gas chromatographic determinations
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
In situ aqueous derivatization as sample preparation technique for gas chromatographic determinations
چکیده انگلیسی


• In situ aqueous derivatization prior to gas chromatography is reviewed.
• Environmental, biological and food matrices are considered.
• Techniques for introduction of derivatives into the chromatograph are specified.

The use of derivatization reactions is a common practice in analytical laboratories. Although in many cases it is tedious and time-consuming, it does offer a good alternative for the determination of analytes not compatible to gas chromatography. Many of the reactions reported in the literature occur in organic medium. However, in situ aqueous derivatization reactions, which can be performed directly in aqueous medium, offer important advantages over those mentioned above, such as no need of a previous extraction step and easy automation. Here we review the most recent developments and applications of in situ aqueous derivatization. The discussion focuses on the derivatization reactions used for the determination of alcohols and phenols, carboxylic acids, aldehydes and ketones, nitrogen-containing compounds and thiols in different aqueous matrices, such as environmental, biological and food samples. Several reactions are described for each functional group (acylation, alkylation, esterification, among others) and, in some cases, the same reagents can be used for several functional groups, such that there is an unavoidable overlap between sections. Finally, attention is also focused on the techniques used for the introduction of the derivatives formed in the aqueous medium into the chromatographic system. The implementation of in situ aqueous derivatization coupled to preconcentration techniques has permitted the enhancement of recoveries and improvements in the separation, selectivity and sensitivity of the analytical methods.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1296, 28 June 2013, Pages 70–83
نویسندگان
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