کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1201231 1493705 2012 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Modelling and optimisation of preparative chromatographic purification of europium
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Modelling and optimisation of preparative chromatographic purification of europium
چکیده انگلیسی

A model commonly used to describe the separation of biomolecules was used to simulate the harsh environment when eluting neodymium, samarium, europium and gadolinium with a hot acid. After calibration, the model was used to optimise the preparative separation of europium, as this is the most valuable of the four elements. A kinetic dispersive model with a Langmuir mobile phase modulator isotherm was used to describe the process. The equilibration constant, the stoichiometric coefficient and the column capacity for the components were calibrated. The model fitted the experimental observations well. Optimisation was achieved using a differential evolution method. As the two objective functions used in optimising the process, productivity and yield, are competing objectives, the result was not a single set point but a Pareto front.


► Modelling of preparative separation of the REE using a strong acid.
► Cerium was a good substitute to the expensive elements in overloaded experiments.
► Optimisation of Eu separation regarding yield and productivity.
► It is possible to model and optimise the harsh system when separating small ions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1220, 13 January 2012, Pages 21–25
نویسندگان
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