کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1203240 965104 2010 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Improved reversed-phase gradient retention modeling
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Improved reversed-phase gradient retention modeling
چکیده انگلیسی

An empirical nonlinear equation is used to describe the relationship between chromatographic retention and solvent composition in both isocratic and gradient chromatography. The integration of the gradient equation can be solved with our equation, allowing a simple transition between isocratic and gradient conditions. Precise interpolation between experimental data points and reasonable extrapolation outside the directly measured data range are possible. Also, the dependence of the parameters of the equation on temperature has been explored, allowing the simultaneous exploration of temperature, gradient starting composition and gradient slopes. A unique quality criterion is used to judge the quality of the separation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1217, Issue 24, 11 June 2010, Pages 3794–3803
نویسندگان
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