کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1203698 | 965122 | 2011 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: High temperature normal phase liquid chromatography of aromatic hydrocarbons on bare zirconia High temperature normal phase liquid chromatography of aromatic hydrocarbons on bare zirconia](/preview/png/1203698.png)
The normal phase HPLC behavior of a bare zirconia column was studied at temperatures up to 200 °C using a hexane mobile phase. The use of elevated column temperatures significantly decreased the retention of twenty five aromatic model compounds according to the van’t Hoff equation (>30-fold decrease for some compounds). Large improvements in peak shape, efficiency (>2.2-fold), aromatic group-type selectivity, and column re-equilibration times (>5-fold) were obtained at elevated temperatures. The thermal decomposition of two polar nitrogen compounds (indole and carbazole) was observed in a hexane/dichloromethane mobile phase at temperatures greater than 100 °C. The first order decomposition of carbazole was studied in further detail.
► Normal phase HPLC on bare zirconia at elevated temperature.
► Temperature decreases retention and improves peak shape and efficiency.
► Aromatic group type selectivity improved with elevated temperature.
► Decomposition of some polar analytes was observed and characterized.
Journal: Journal of Chromatography A - Volume 1218, Issue 44, 4 November 2011, Pages 7948–7955