کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1204099 | 965140 | 2010 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Identification and enantioselective gas chromatographic mass-spectrometric separation of O-desmethylnaproxen, the main metabolite of the drug naproxen, as a new environmental contaminant
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Identification and enantioselective gas chromatographic mass-spectrometric separation of O-desmethylnaproxen, the main metabolite of the drug naproxen, as a new environmental contaminant Identification and enantioselective gas chromatographic mass-spectrometric separation of O-desmethylnaproxen, the main metabolite of the drug naproxen, as a new environmental contaminant](/preview/png/1204099.png)
چکیده انگلیسی
O-Desmethylnaproxen (2-(6-hydroxynaphthalen-2-yl)propanoic acid) was identified in 10 different water samples from Germany and Pakistan. In the Pakistan samples it was found in all samples, surface water and effluents, exhibiting estimated concentrations between 0.04 and 1.36 μg/L. In Germany it was only encountered in the STP-effluent with an average concentration of 0.23 μg/L. Furthermore, enantioselective GC analyses revealed differences in the enantiomeric ratios found in Germany and Pakistan. To the best of our knowledge this is the first report on the identification of O-desmethylnaproxen, the main metabolite of the drug naproxen, in environmental samples.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1217, Issue 3, 15 January 2010, Pages 419–423
Journal: Journal of Chromatography A - Volume 1217, Issue 3, 15 January 2010, Pages 419–423
نویسندگان
Stephanie Selke, Markus Scheurell, Muhammad Raza Shah, Heinrich Hühnerfuss,