کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1205810 1493727 2008 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evaluation of chromatographic performance of various packing materials having different structural characteristics as stationary phase for fast high performance liquid chromatography by new moment equations
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Evaluation of chromatographic performance of various packing materials having different structural characteristics as stationary phase for fast high performance liquid chromatography by new moment equations
چکیده انگلیسی

Chromatographic performance of various separation media having different structural characteristics as the stationary phase for fast HPLC was quantitatively evaluated by using the new moment equations recently developed with considering the shape and porous structure of the packing materials. Four types of separation media, i.e., full-porous, partially porous (pellicular or shell) type, and non-porous spherical particles and full-porous cylindrical fiber, were chosen as examples. The moment equations were used for predicting the chromatographic behaviors of benzene under hypothetical RPLC conditions. The overall performance of the four types of packing materials as the separation media for fast HPLC was compared with each other from the viewpoint of the peak capacity, which depends on both the retention equilibrium and the mass transfer kinetics. It seems that the full-porous cylindrical fiber and the pellicular type spherical particle are more preferable than the others, i.e., the full-porous and non-porous spherical particles. Now we can use the new moment equations for the quantitative prediction of the chromatographic behaviors of the various packing materials on the basis of a related experimental information and for the evaluation of their performance from various chromatographic points of view. The new moment equations are effective not only for the detailed analyses of chromatographic behaviors but also for the preliminarily evaluation of new types of separation media for fast HPLC.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1183, Issues 1–2, 7 March 2008, Pages 49–64
نویسندگان
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