کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1206397 965232 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Analysis of whole congener mixtures of polybromodiphenyl ethers by gas chromatography–mass spectrometry in both environmental and biological samples at femtogram levels
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Analysis of whole congener mixtures of polybromodiphenyl ethers by gas chromatography–mass spectrometry in both environmental and biological samples at femtogram levels
چکیده انگلیسی

A sensitive and selective method for the determination of the whole congener distribution of polybromodiphenyl ethers in environmental and biological samples in one single instrumental run is described. The method is based on gas chromatography coupled to low-resolution mass spectrometry in negative ion chemical ionization mode. It allows determination of these compounds at concentration levels lower than 10−14 g. A programmed temperature vaporization injector has been used to ensure maximum compound transfer to the chromatographic column while maintaining low thermal degradation levels of the more brominated congeners. Selectivity was increased by modification of the MS source parameters for optimization of the abundance of the high mass fragment ions. Under optimized condition, good repeatability (1.7–9.1%) and reproducibility (4.1–20%), and low detection limits, ranging between 1.5 and 15 pg ml−1, were obtained. These features afforded reliable quantification of these compounds in snow and human samples at the concentrations in which these compounds are found.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1216, Issue 25, 19 June 2009, Pages 5045–5051
نویسندگان
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