کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1206709 1493742 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Extraction of acidic degradation products of organophosphorus chemical warfare agents: Comparison between silica and mixed-mode strong anion-exchange cartridges
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Extraction of acidic degradation products of organophosphorus chemical warfare agents: Comparison between silica and mixed-mode strong anion-exchange cartridges
چکیده انگلیسی

The analysis of alkyl alkylphosphonic acids (AAPAs) and alkylphosphonic acids (APAs), the hydrolyzed products of nerve agents, constitutes an important aspect for verifying the compliance to the Chemical weapons convention (CWC). This work devotes on the development of solid-phase extraction method using polymeric mixed-mode strong anion-exchange (Oasis MAX) cartridges for extraction of AAPAs and APAs from water. The extracted analytes were analyzed by GC–MS under full scan and selected ion monitoring mode. The extraction efficiencies of MAX and silica-based anion-exchange cartridges were compared, and results revealed that MAX sorbents yielded better recoveries. Extraction parameters, such as loading capacity, extraction solvent, its volume, and washing solvent were optimized. Best recoveries were obtained using 1 mL of acidic methanol (0.1 M), and limits of detection could be achieved up to 5 × 10−4 μg mL−1 (in SIM) and 0.05 μg mL−1 in full scan mode. The method was successfully employed for the detection and identification of alkylphosphonic acids present in soil sample sent by the Organization for Prohibition of Chemical Weapons (OPCW) in the official proficiency tests.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1161, Issues 1–2, 17 August 2007, Pages 98–104
نویسندگان
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