کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1206878 | 1493743 | 2007 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Characterization of the retention behavior of organic and pharmaceutical drug molecules on an immobilized artificial membrane column with the Abraham model
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Characterization of the retention behavior of organic and pharmaceutical drug molecules on an immobilized artificial membrane column with the Abraham model Characterization of the retention behavior of organic and pharmaceutical drug molecules on an immobilized artificial membrane column with the Abraham model](/preview/png/1206878.png)
چکیده انگلیسی
Data have been compiled from the published literature on the retention factors of 174 organic compounds and drug molecules eluted from a Regis Technologies IAM.PC.DD2 HPLC column using an aqueous mobile phase buffered in the pH range of pH 6.5–7.5. The logarithms of the retention factors are correlated with the Abraham solvation parameter model. The derived correlation contains the five Abraham solute descriptors plus two additional indicator descriptors (ICOOH and Iamine) that would be needed whenever carboxylic acid and alkylamine solutes are eluted in ionic form. The derived correlation describes the experimental capacity data of 174 neutral, acidic and basic compounds to within 0.21 log units.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1160, Issues 1–2, 10 August 2007, Pages 235–245
Journal: Journal of Chromatography A - Volume 1160, Issues 1–2, 10 August 2007, Pages 235–245
نویسندگان
Laura Sprunger, Brooke H. Blake-Taylor, Angeline Wairegi, William E. Acree Jr., Michael H. Abraham,