Predicting the chromatographic retention of polymers: Application of the polymer model to poly(styrene/ethylacrylate)copolymers

► Statistical SEA-copolymers behave in gradient and isocratic liquid chromatography similar to homopolymers. ► Critical conditions for SEA-copolymers exist. ► Critical conditions can be estimated from a single gradient experiment. ► The applied polymer model allows quantitative predictions of the elution volumes.