کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1207806 1645348 2008 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Comparison of microdialysis with solid-phase microextraction for in vitro and in vivo studies
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Comparison of microdialysis with solid-phase microextraction for in vitro and in vivo studies
چکیده انگلیسی
Microdialysis (MD) and solid-phase microextraction (SPME) methods have been developed and compared through in vitro and in vivo studies. For in vitro study, both methods offered accurate and precise results for complex sample matrices by standard addition method. Compared to MD, the fully automated SPME procedure offered several advantages including high-throughput and more efficient sampling, less labor intensity, and capability for batch analysis. For in vivo study, although both techniques provided sampling with minimal perturbation to the system under study, SPME was more sensitive, precise and accurate, suitable for field sampling and had a wider application than MD. It demonstrated that SPME has the potential to replace MD for in vivo study.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volumes 1196–1197, 4 July 2008, Pages 46-56
نویسندگان
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