Multiresidue determination of fluoroquinolones, organophosphorus and N-methyl carbamates simultaneously in porcine tissue using MSPD and HPLC–DAD

Increasing concerns on public health safety have led researchers to develop efficient methods to characterize veterinary drugs and pesticides residues simultaneously in animal products. This investigation presents a simple and rapid method to determine five types of fluoroquinolones (FQs), organophosphorus (OP) and N-methyl carbamates (NMCs) in porcine tissue simultaneously with the use of matrix solid-phase dispersion (MSPD), high performance liquid chromatography (HPLC) and diode array detection (DAD). The results show a recovery ratio of 60.1–107.7% with satisfactory relative standard deviations. The limits of detection (LOD) in porcine tissue are between 9 and 22 μg/kg. The applicability of the method to the multiresidue analysis in porcine tissue is reported in this contribution.