On-fiber furan formation from volatile precursors: A critical example of artefact formation during Solid-Phase Microextraction

► Considerable amounts of furan can be formed on the SPME fiber during thermal desorption of volatile furan precursors. ► The artefactual furan formation increased with increasing desorption time, but especially with increasing desorption temperature. ► The artefactual formation of furan may influence a high amount of literature data and current investigations.