کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1222513 | 967866 | 2008 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Structural elucidation of a PDE-5 inhibitor detected as an adulterant in a health supplement
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Structural elucidation of a PDE-5 inhibitor detected as an adulterant in a health supplement Structural elucidation of a PDE-5 inhibitor detected as an adulterant in a health supplement](/preview/png/1222513.png)
چکیده انگلیسی
A PDE-5 inhibitor was detected and isolated from a health supplement claimed to be a preparation of fresh oyster extracts and be able to promote and support healthy sexual function and endurance, etc. The structure of this PDE-5 inhibitor was elucidated using LC–UV, LC–TOF-MS, MS–MS, IR spectroscopy, and 2D NMR. It was characterized as 8-(2-(4-(hydroxymethyl)piperidin-1-yl)benzylamino)-3-ethyl-1H-imidazo[4,5-g]quinazoline-2(3H)-thione, a compound reported to be a PDE-5 inhibitor.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 48, Issue 4, 1 December 2008, Pages 1070–1075
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 48, Issue 4, 1 December 2008, Pages 1070–1075
نویسندگان
Xiaowei Ge, Min-Yong Low, Peng Zou, Li Lin, Sharon Oh Sze Yin, Bosco C. Bloodworth, Hwee-Ling Koh,