کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1222811 967871 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Development of a liquid chromatography–tandem mass spectrometry method for an euthanasic veterinarian drug: Tanax®
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Development of a liquid chromatography–tandem mass spectrometry method for an euthanasic veterinarian drug: Tanax®
چکیده انگلیسی

A development of a rapid and sensitive LC–MS/MS method for the simultaneous detection of active ingredients of the euthanasic veterinarian drug Tanax® mixture is described.The method proposed, with a retention time of few minutes (6 min) was developed for an equine serum sample with solid-phase extraction (S.P.E). This S.P.E. procedure has been revealed useful for the determination of very low concentrations of Tanax® analytes (0.05–1 ng/ml).The method was validated in terms of specificity/selectivity, sensitivity, recovery and precision.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 48, Issue 3, 4 November 2008, Pages 902–908
نویسندگان
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