کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1224460 967923 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Characterization of polymethoxylated flavones in Fructus aurantii by liquid chromatography with atmospheric pressure chemical ionization combined with tandem mass spectrometry
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Characterization of polymethoxylated flavones in Fructus aurantii by liquid chromatography with atmospheric pressure chemical ionization combined with tandem mass spectrometry
چکیده انگلیسی

Atmospheric pressure chemical ionization mass spectrometry (APCI-MS) was operated in positive mode (PI) to characterize polymethoxylated flavonoids (PMFs) through its specific radical cations by collision-induced dissociation (CID). The fragments of [M + H − n × 15]+ produced by loss of one or more methyl group from the protonated molecule, as well as [M + H − 29]+, [M + H − 31]+, [M + H − 33]+, [M + H − 43]+, [M + H − 46]+, and [M + H − 61]+ fragment ions were detected, which were diagnostic for the polymethoxylated species, and could be adopted to form the multiple MS (MSn) “fingerprint” of PMFs. Based on this “fingerprint”, 29 PMFs were screened out from extracts of Fructus aurantii, among which two of them were identified as sinensetin and tangeretin. It was proved that the PI was suitable for structural characterization of PMFs by APCI-MSn.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 43, Issue 5, 11 April 2007, Pages 1692–1699
نویسندگان
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