کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1224606 967927 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Application of an improved column characterisation system to evaluate the within and between batch variability
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Application of an improved column characterisation system to evaluate the within and between batch variability
چکیده انگلیسی

The selection of a reversed-phase liquid chromatographic column with suitable selectivity for a particular separation is difficult if the brand name of the column is not known. A project to develop a chromatographic test procedure to characterize reversed-phase liquid chromatography C18 columns was started earlier and resulted in a fast, simple, repeatable and reproducible test procedure using four column parameters. Here, this procedure is used to evaluate the diversity of columns originating from the same batch as well as from different batches. The determination of one of the parameters, the retention factor of 2,2′-dipyridyl, was improved and a simplified test procedure is proposed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 44, Issue 3, 27 July 2007, Pages 634–639
نویسندگان
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