Ultrasound-mediated structural changes in cells revealed by FTIR spectroscopy: A contribution to the optimization of gene and drug delivery

► FTIR reveals the ultrasound-induced structural changes in cells. ► Different effects due to ultrasound in two cell lines. ► The statistical comparison between FTIR results in two cell lines. ► Ultrasound-induced cytotoxic effect in Jurkat cells revealed by CBMN assay. ► Characterization of ultrasound field to estimate in situ exposure levels in cells.