کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1242109 | 1495817 | 2014 | 7 صفحه PDF | دانلود رایگان |
• We developed a new method for analyzing trace indicator toxaphene congeners in soil.
• GC×GC–MS was used to effectively separate and determine the toxaphene components.
• The detection limits for Parlar 26, 50, and 62 were ranged from 0.4 to 1.0 pg/g.
Toxaphene, which is a broad spectrum chlorinated pesticide, is a complex mixture of several hundred congeners, mainly polychlorinated bornanes. Quantifying toxaphene in environmental samples is difficult because of its complexity, and because each congener has a different response factor. Toxaphene chromatograms acquired using one-dimensional gas chromatography (1DGC) show that this technique cannot be used to separate all of the toxaphene congeners. We developed and validated a sensitive and quantitative method for determining three indicator toxaphene congeners in soil using an isotope dilution/comprehensive two-dimensional gas chromatography–tandem mass spectrometry (GC×GC–MS). The samples were extracted using accelerated solvent extraction, and then the extracts were purified using silica gel columns. 13C10-labeled Parlar 26 and 50 were used as internal standards and 13C10-labeled Parlar 62 was used as an injection standard. The sample extraction and purification treatments and the GC×GC–MS parameters were optimized. Subsequently the samples were determined by GC×GC–MS. The limits of detection for Parlar 26, 50, and 62 were 0.6 pg/g, 0.4 pg/g, and 1.0 pg/g (S/N=3), respectively, and the calibration curves had good linear correlations between 50 and 1000 μg/L (r2>0.99). Comprehensive two-dimensional GC gave substantial improvements over one-dimensional GC in the toxaphene analysis. We analyzed soil samples containing trace quantities of toxaphene to demonstrate that the developed method could be used to analyze toxaphene in environmental samples.
Journal: Talanta - Volume 118, 15 January 2014, Pages 210–216