کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1245129 969712 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sensitivity enhancement of SPR biosensor with silver mirror reaction on the Ag/Au film
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Sensitivity enhancement of SPR biosensor with silver mirror reaction on the Ag/Au film
چکیده انگلیسی

Based on well-known silver mirror reaction the Ag film was formed on Au film modified by self-assembled monolayer (SAM) of 1,6-hexanedithiol (HDT). The sensitivity of the biosensor based on this Ag/Au film is enhanced compared to that based on Au film. When the surface plasmon resonance (SPR) biosensor based on this Ag/Au film was used to determine human IgG, the range of concentrations of human IgG that could be determined is 0.30–40.00 μg mL−1. The lowest concentration (0.30 μg mL−1) that could be detected was about 8 times lower than that obtained by the biosensor without modification by Ag film (2.50 μg mL−1), which demonstrated that the biosensor based on Ag/Au film could make the resonant wavelength move to longer wavelength following with the sensitivity enhancement of the SPR biosensor.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Talanta - Volume 78, Issue 1, 15 April 2009, Pages 265–269
نویسندگان
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