A study of the analytical behaviour of selected psycho-active drugs using liquid chromatography, ion trap mass spectrometry, gas chromatography and polarography and the construction of an appropriate database for drug characterisation

This paper provides analytical chemical information on a range of psycho-active drugs. This analytical chemical information on liquid chromatography–electrospray ionisation-mass spectrometry (HPLC–ESI-MS), ion trap mass spectrometry (ESI–MSn), gas chromatography–flame ionisation detection (GLC–FID) and polarographic behaviour is then incorporated into a database which is of use in drug characterisation. Application is found in the determination of selected drug compounds in hair samples.