کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1248967 | 970492 | 2008 | 13 صفحه PDF | دانلود رایگان |
In the past few years, low-pressure gas chromatography (LP-GC) has been applied for the fast analysis of various pollutants in different environmental and food matrices. A typical LP-GC set-up involves the use of a short microbore column (typically 0.5–1 m × 0.10 mm internal diameter) at the injector side connected with a zero dead-volume connector to a short megabore column (typically 10 m × 0.53 mm) to be used with higher gas velocities. This set-up maintains atmospheric injection conditions, while the analytical column is operated under low-pressure conditions that are compatible with mass-spectrometer analyzers. Although the use of LP-GC results in a loss of separation efficiency, it offers a 3–5-fold reduction in analysis time for organic compounds and thus increased sample throughput and enhancement of the signal-to-noise ratio leading to improved detection limits. Considering the significance of, and the potential interest in, this topic, this review briefly describes the concept of LP-GC. Furthermore, we explore recent developments and applications of LP-GC, with a focus on the use of various column systems and analyzers. Finally, we critically evaluate the prospects for, and the limitations of, LP-GC.
Journal: TrAC Trends in Analytical Chemistry - Volume 27, Issue 4, April 2008, Pages 291–303