کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1251667 | 1496289 | 2015 | 8 صفحه PDF | دانلود رایگان |
• Exposure to fullerenes (C60) can lead to damaging effects on biomembranes.
• C60 causes increase in the bilayer undulations (∼20%).
• C60 enhances the mean inter-bilayer separation (∼15%).
• C60-incorporation increased the linear expansion coefficient.
• Addition of C60 causes a drop in the bending rigidity of the bilayers (20–40%).
The coupling of fullerene (C60) to the structure and elasticity of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine bilayers has been explored by synchrotron small angle X-ray scattering. Multilamellar vesicles were loaded with 0, 2 and 10 mol.% of C60 and studied in a temperature range from 15 to 65 °C. The addition of C60 caused an increase in the bilayer undulations (∼20%), in the bilayer separation (∼15%), in the linear expansion coefficient and caused a drop in the bending rigidity of the bilayers (20–40%). Possible damaging effects of fullerene on biomembranes are mainly discussed on the basis of altered bilayer fluidity and elasticity changes.
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Journal: Chemistry and Physics of Lipids - Volume 188, May 2015, Pages 46–53