کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1299947 1498819 2008 31 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Metal catalyzed asymmetric cyanation reactions
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Metal catalyzed asymmetric cyanation reactions
چکیده انگلیسی

Chiral cyanohydrins are versatile building blocks for pharmaceuticals, agrochemicals and specialty materials. A number of efficient and successful synthetic methods have been developed however, the chiral catalytic method is one of the most attractive strategies where asymmetric addition of different source of cyanide to the carbonyl group of aldehydes and ketones was affected with the help of a chiral metal complex. This review would discuss the various methods for catalytic asymmetric synthesis of cyanohydrins derived from both aldehydes and ketones using different source of cyanide. The emphasis would be given to chiral Lewis acid metal complexes as efficient catalysts for cyanation reaction with the probable mechanism, wherever necessary.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Coordination Chemistry Reviews - Volume 252, Issues 5–7, March 2008, Pages 593–623
نویسندگان
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