کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1299950 | 1498819 | 2008 | 43 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis of chiral pharmaceutical intermediates by biocatalysis
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی معدنی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis of chiral pharmaceutical intermediates by biocatalysis Synthesis of chiral pharmaceutical intermediates by biocatalysis](/preview/png/1299950.png)
چکیده انگلیسی
Chirality is a key factor in the safety and efficacy of many drug products and thus the production of single enantiomers of drug intermediates has become increasingly important in the pharmaceuticals industry. There has been an increasing awareness of the enormous potential of microorganisms and enzymes derived therefrom for the transformation of synthetic chemicals with high chemo-, regio- and enatio-selectivities. In this article, biocatalytic processes are described for the synthesis of chiral intermediates for pharmaceuticals.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Coordination Chemistry Reviews - Volume 252, Issues 5–7, March 2008, Pages 659–701
Journal: Coordination Chemistry Reviews - Volume 252, Issues 5–7, March 2008, Pages 659–701
نویسندگان
Ramesh N. Patel,