کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1307725 975152 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis, characterization and bioactivity of a novel 18-metallacrown-6: [Mn(pcshz)(CH3OH)]6 · 4CH3OH · 4H2O
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Synthesis, characterization and bioactivity of a novel 18-metallacrown-6: [Mn(pcshz)(CH3OH)]6 · 4CH3OH · 4H2O
چکیده انگلیسی

The reaction of N-propionyl-5-chlorosalicylhydrazide (H3pcshz) with Mn(OAc)2 · 4H2O in methanol solution gives a novel 18-metallacrown-6 [Mn(pcshz)(CH3OH)]6 · 4CH3OH · 4H2O (1). The structure of 1 has been determined by X-ray diffraction and it crystallizes in the monoclinic system and space group P2(1)/n. The ring of the metallacrown is consisted of six interlink [Mn–N–N] repeated units through hydrazide N–N group bridging the ring manganese ions. And the ligand enforces the metal ions to form the stereochemistry as a propeller configuration with alternation Λ/Δ form. The largest diameters of the disc-shaped hexanuclear ring are about 8.82 Å at entrance, 9.83 Å at the central of the cavity, respectively. The solution integrity and stability of the metallacrown was studied by electrospray ionization (ESI)-MS and UV–Vis spectroscopy. The results show it is soluble and stable in methanol. Antibacterial screening data indicate the forming of the complex weakens dramatically the antibacterial activity of the ligand H3pcshz except for Eschericha coli.

A novel macrocyclic hexanuclear Mn(III) 18-metallacrown-6 compound, [Mn(pcshz)(CH3OH)]6 · 4CH3OH · 4H2O, has been prepared using a trianionic pentadentate ligand N-propionyl-5-chlorosalicylhydrazidate (pcshz3−) and characterized by X-ray diffraction. The ring of the metallacrown remains integrity and stable in methanol. Antibacterial screening data showed the metallacrown has strong antimicrobial activity against Eschericha coli.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Inorganica Chimica Acta - Volume 360, Issue 10, 2 July 2007, Pages 3341–3346
نویسندگان
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