Non-covalent (iso)guanosine-based ionophores for alkali(ne earth) cations

The alkali(ne earth) cation extraction affinity/selectivity of three lipophilic (iso)guanosine-based self-assembled ionophores is compared. This allows for the direct comparison of the metal ion complexation by single guanosine quartets, (double) guanosine quadruplexes, and isoguanosine based decameric assemblies.