New non-aggregating bivalent cis-ML2 (MÂ =Â Pd, Pt; LÂ =Â pivaloylcyanoxime)

The 1-oximino-1-cyano-3-t-butyl-ketone (pivaloyl-cyanoxime), HPiCO, and its two new bivalent Pd, Pt complexes of M(PiCO)2 composition were synthesized and characterized using UV-Vis, IR spectroscopic methods, TG/DSC and X-ray analysis. An assessment of in vitro cytotoxicity of these new complexes was carried out on WiDR human cancer cell line with cisplatin used as a positive control.28