کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1308714 | 975180 | 2009 | 4 صفحه PDF | دانلود رایگان |
A platinum(II) complex Pt(phen)CCC6H4CHO has been demonstrated as a highly selective phosphorescent chemodosimeter for cysteine and homocysteine. Upon addition of homocysteine or cysteine to its acetonitrile–water solution, an evident luminescent color variation from green to orange was observed. This red-shift of phosphorescence emission could be attributed to formation of a thiazinane through a selective reaction of aldehyde group of Pt(phen)CCC6H4CHO with cysteine/homocysteine, which was confirmed by 1H NMR investigation and density functional theory (DFT) calculations. The further selectivity investigation indicates that it displays high selectivity for homocysteine and cysteine, and therefore can be utilized as cysteine/homocysteine phosphorescent chemodosimeter.
The original solution of complex Pt(phen)CCC6H4CHO (1) in acetonitrile–water (40 μM, 4:1 v/v) showed a intensive phosphorescent emission centered at 510 nm. Upon addition of homocysteine or cysteine to this acetonitrile–water solution, an evident luminescent color variation from green to orange was observed.Figure optionsDownload as PowerPoint slide
Journal: Inorganica Chimica Acta - Volume 362, Issue 8, 1 June 2009, Pages 2577–2580