کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1308833 975186 2009 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Photoactive trans ammine/amine diazido platinum(IV) complexes
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Photoactive trans ammine/amine diazido platinum(IV) complexes
چکیده انگلیسی

The synthesis and characterisation of eight new octahedral PtIV complexes of the type trans,trans,trans-[Pt(N3)2(OH)2(NH3)(Am)] where Am = methylamine (2), ethylamine (4), thiazole (6), 2-picoline (8), 3-picoline (10), 4-picoline (12), cyclohexylamine (14), and quinoline (16) are reported, including the X-ray crystal structures of complexes 2, 8, and 14 as well as that of two of the precursor PtII complexes (trans-[Pt(N3)2(NH3)(methylamine)] (1) and trans-[Pt(N3)2(NH3)(cyclohexylamine)] (13)). Irradiation with UVA light rapidly induces loss in intensity of the azide-to-PtIV charge-transfer bands and gives rise to photoreduction of platinum. These complexes have potential for use as photoactivated anticancer agents.

New all-trans ammine/amine diazido dihydroxo octahedral PtIV complexes are readily photoactivated and have potential for use as photochemotherapeutic anticancer agents.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Inorganica Chimica Acta - Volume 362, Issue 3, 20 February 2009, Pages 811–819
نویسندگان
, , , , ,