کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1316405 | 976456 | 2007 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Curcumin and cyclopalladated complexes: A recipe for bifunctional biomaterials
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی معدنی
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
The first examples of binuclear and mononuclear ortho-palladated complexes based on a functionalized 2-phenylquinoline ligand have been synthesized and fully characterized. Conjugating cyclopalladated fragments to curcumin family biologically active β-diketones gives in one single molecule two different functionalities. The structural variations based on the curcuminoid structure have been tested for their in vitro cytotoxic activity. The activity of complexes comprised of a cyclopalladated fragment conjugated to functionalized bioactive ligands, represents the potential of organometallic systems in generating new bifunctional biomaterials.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Inorganic Biochemistry - Volume 101, Issue 7, July 2007, Pages 1013–1022
Journal: Journal of Inorganic Biochemistry - Volume 101, Issue 7, July 2007, Pages 1013–1022
نویسندگان
Daniela Pucci, Rossana Bloise, Anna Bellusci, Sergio Bernardini, Mauro Ghedini, Sante Pirillo, Alessandra Valentini, Alessandra Crispini,