کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1316875 | 976489 | 2009 | 10 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Cell signaling, beyond cytosolic calcium in eukaryotes Cell signaling, beyond cytosolic calcium in eukaryotes](/preview/png/1316875.png)
Calcium functions as a secondary messenger within the cytosols of eukaryotes. This serves as a reference point to evaluate three related questions:1.Calcium, as well as cyclic AMP, also functions as a paracrine messenger; how specific and extensive is this use?2.Calcium binding proteins and calcium extrusion mechanisms have been identified in prokaryotes; does it function as a messenger?3.The concentrations of other divalent cations, especially zinc and magnesium, are well regulated and perturbations have specific physiological impacts; are these divalents involved in information transfer?Exploration of these three interrelated questions indicates the importance of more sensitive techniques and of a refined concept of information transfer and transduction.
Journal: Journal of Inorganic Biochemistry - Volume 103, Issue 1, January 2009, Pages 77–86