Differential effects of Co(III), Ni(II), and Ru(III) amine complexes on Sindbis virus

Structurally variable transition metal complexes show differential effects against Sindbis infected BHK cells. Although data indicate anti-viral activity for some structural variations, it appears that [Co(NH3)6]Cl3 is unique in its ability to significantly enhance cell survival and decrease viral expression. [Co(NH3)6]Cl3 shows activity against Adenovirus supporting its broad-spectrum potential.