Copper catalyzed synthesis of 1-aryl-1,2,3-triazoles from aryl iodides, alkynes, and sodium azide

• The synthesis of 1-aryl 1,2,3-triazoles using porous Cu (0) has been reported.
• Porous Cu was found to be a highly efficient heterogeneous catalyst.
• The spent catalyst can be easily recovered and reused.

Aryl azides were synthesized using heterogeneous porous Cu (0) catalyst via a coupling reaction of aryl iodides with sodium azide under mild conditions. Under the same conditions, one-pot Cu-catalyzed azide–alkyne cycloaddition of aryl iodides, alkynes, and sodium azide yielded 1-aryl-1,2,3-triazoles.

Porous Cu (0) was found to be a highly efficient heterogeneous catalyst for the one-pot synthesis of 1-aryl 1,2,3-triazoles from aryl iodides, alkynes, and sodium azide. The porous Cu (0) catalyst can be easily recovered and reused for five cycles with consistent activity.Figure optionsDownload as PowerPoint slide