Polystyrene supported thiopseudourea Pd(II) complex: Applications for Sonogashira, Suzuki-Miyaura, Heck, Hiyama and Larock heteroannulation reactions

• The synthesized polymer supported thiopseudourea palladium complex was fully characterized.
• This complex exhibited efficient catalytic activity in C–C cross coupling and heteroannulation reactions.
• The catalyst can be reused several times with slight change in activity for Sonogashira and Suzuki cross coupling reactions.

A new polystyrene supported thiopseudourea palladium(II) complex (3) is found to be a highly active catalyst for the copper-free Sonogashira, Suzuki, Heck, Hiyama and Larock heteroannulation reactions of aryl halides. All the reactions proceeded well affording the corresponding cross-coupling products in good to excellent yields. Further, the catalyst showed excellent recyclability without any significant loss in its activity.

The polymer supported thiopseudourea palladium(II) complex (3) is found to be an efficient catalyst for C–C cross coupling reactions of aryl halides and Larock heteroannulation reaction of 2-iodoaniline. It has high thermal stability, recyclability and good catalytic activity. Figure optionsDownload as PowerPoint slide