کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1322857 977252 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Arene–ruthenium complexes with ferrocene-derived ligands: Synthesis and characterization of complexes of the type [Ru(η6-arene)(NC5H4CH2NHOC-C5H4FeC5H5)Cl2] and [Ru(η6-arene)(NC3H3N(CH2)2O2C–C5H4FeC5H5)Cl2]
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Arene–ruthenium complexes with ferrocene-derived ligands: Synthesis and characterization of complexes of the type [Ru(η6-arene)(NC5H4CH2NHOC-C5H4FeC5H5)Cl2] and [Ru(η6-arene)(NC3H3N(CH2)2O2C–C5H4FeC5H5)Cl2]
چکیده انگلیسی

Arene–ruthenium complexes of general formula [Ru(η6-arene)(L)Cl2] where L = NC5H4CH2NHOC–C5H4FeC5H5, arene = p-iPrC6H4Me (1) or C6Me6 (2); L = NC3H3N(CH2)2O2C–C5H4FeC5H5, arene = p-iPrC6H4Me (3) or C6Me6 (4), and diruthenium–arene complexes of general formula [Ru(η6-arene)Cl2]2(L) where L = 1,1′-(NC5H4CH2NHOC)2-C5H4FeC5H4, arene = p-iPrC6H4Me (5) or C6Me6 (6); L = 1,1′-(NC3H3N(CH2)2O2C)2–C5H4FeC5H4, arene = p-iPrC6H4Me (7) or C6Me6 (8) have been synthesized and characterized. The molecular structures of 1 and 3 were confirmed by single-crystal X-ray diffraction. The in vitro anticancer activities of complexes 1–8 have been studied comparatively to the uncoordinated ligands. The complexes exhibit fairly low cytotoxicities in comparison to related ferrocene-derived arene–ruthenium complexes.

A series of eight arene–ruthenium complexes containing ferrocene-derived ligands have been synthesized and characterized. The in vitro anticancer activities of these complexes have been studied comparatively to the uncoordinated ligands. The complexes exhibit fairly low cytotoxicities in comparison to related ferrocene-derived arene–ruthenium complexes.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Organometallic Chemistry - Volume 694, Issue 6, 15 March 2009, Pages 855–861
نویسندگان
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