Hydroxyl and amino functionalized cyclometalated Ir(III) complexes: Synthesis, characterization and cytotoxicity studies

• A series of Ir(III) complexes were successfully synthesized and characterized.
• Two of the complexes were structurally characterized via X-ray crystallography.
• The emission of the complexes could be switched off or on in acid or base solution.
• The complexes could be potentially used for the luminescence pH sensors.
• Some of the complexes have promising potential as specific cell-imaging agents.

A series of Ir(III) complexes (CˆN)2Ir(NˆN) (NˆN are 4,4′-dihydroxy-2,2′-bipyridine and 4,4′-diamino-2,2′-bipyridine, and CˆN are phenylpyridine, benzo[h]quinolone, and 2-phenylquinoline) were synthesized and characterized. Two of the complexes were structurally characterized via X-ray crystallography. The photophysical and photochemical properties of these complexes were studied. Preliminary studies of their applications on pH sensing, and cell imaging were also performed.

A series of Ir(III) complexes with amino or hydroxyl groups were synthesized and characterized. Two of the complexes were structurally characterized via X-ray crystallography. The photophysical and photochemical properties of these complexes were studied. Preliminary studies of their applications on pH sensing, and cell imaging were also performed.Figure optionsDownload as PowerPoint slide