کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1323272 | 977276 | 2015 | 7 صفحه PDF | دانلود رایگان |
• We have prepared functionalized benzoboroxoles via reductive amination protocol.
• We have also prepared N-nitrosoaminobenzoboroxoles and benzoboroxolylureas.
• These benzoboroxoles have been further evaluated as potential anti-cancer agents.
Several aminobenzoboroxole derivatives have been prepared starting from o-boronobenzaldehyde employing reductive amination protocol. The corresponding aminobenzoboroxole derivatives have been further functionalized as N-nitrosoaminobenzoboroxoles as well as N-benzoboroxolylureas. These derivatives have been evaluated for their anti-cancer activity on human pancreatic cancer MIAPaCa-2 and human breast cancer MDA-MB-231 cell lines. 2015 Elsevier Ltd. All rights reserved.
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Journal: Journal of Organometallic Chemistry - Volume 798, Part 1, 1 December 2015, Pages 125–131